Colonoscopy: A Diagnostic Test for Early Colon Cancer Diagnosis

Ikalo David Oseghale *

Department of Biochemistry, University of Benin, Benin City, Nigeria.

Godwin Mmaduabuchi Ikokwu

Faculty of Pharmacy, University of Benin, Benin City, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

Colonoscopy is a medical test to help find potential problems, such as colorectal cancer or polyps. Polyps are small growths, they are not cancer, but they can turn into cancer. Data from the World Health Organization (WHO), shows that Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths, the most common cancers are breast, lung, colon and rectum and prostate cancers. Also, the WHO data shows that colorectum (colon and rectum) cancer alone in 2020 had 1.93 million cases and resulted in 916,000 deaths. Data from the World Cancer Research Fund International (WCRF) showed that Colorectal cancer is the 3rd most common cancer worldwide. It is the 3rd most common cancer in men and the 2nd most common cancer in women. And lastly, data from the American Cancer Society (ACS) estimates that the number of colorectal cancers in the United States for 2023 are 106,970 new cases of colon cancer, and 46,050 new cases of rectal cancer. Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men and 1 in 26 for women, however, each person’s risk might be higher or lower than this, depending on their risk factors for colorectal cancer. In the United States, colorectal cancer is the third leading cause of cancer-related deaths in both men and women, and it’s the second most common cause of cancer deaths when numbers for men and women are combined. It’s expected to cause about 52,550 deaths during 2023. This article was written with the aim of explaining and providing up-to-date information on the progress made in the field of colonoscopy and its use in diagnosing colorectal/colon cancer.

Keywords: Colorectal cancer, colonoscope, colonoscopy, colon, polyps, cancer, rectum


How to Cite

Oseghale , Ikalo David, and Godwin Mmaduabuchi Ikokwu. 2023. “Colonoscopy: A Diagnostic Test for Early Colon Cancer Diagnosis”. International Research Journal of Oncology 6 (1):28-42. https://journalirjo.com/index.php/IRJO/article/view/121.

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References

Rex DK, Johnson DA, Anderson JC, Schoenfeld PS, Burke CA, Inadomi JM. American College of Gastroenterology guidelines for colorectal cancer screening 2008. Am J Gastroenterol. 2009;104(3): 739-50. DOI: 10.1038/ajg.2009.104

Ko CW, Riffle S, Michaels L, Morris C, Holub J, Shapiro JA et al. Serious complications within 30 days of screening and surveillance colonoscopy are uncommon. Clin Gastroenterol Hepatol. 2010;8(2):166-73. DOI: 10.1016/j.cgh.2009.10.007

Hazewinkel Y, Dekker E. Colonoscopy: Basic principles and novel techniques. Nat Rev Gastroenterol Hepatol. 2011;8(10): 554-64. DOI: 10.1038/nrgastro.2011.141

Ray-Offor E, Abdulkareem FB. Screening colonoscopy in Port Harcourt, Nigeria. Gastroenterol Insights. 2019;10(1):7987. DOI: 10.4081/gi.2019.7987

Lee SH, Park YK, Lee DJ, Kim KM. Colonoscopy procedural skills and training for new beginners. World J Gastroenterol. 2014;20(45):16984-95. DOI: 10.3748/wjg.v20.i45.16984

Schmidt TD. Colonoscopy. Encyclopedia of gastroenterology. 2004;449-56.

Weinstock LB. Body positions for colonoscopy: Value of trendeleburg. gastrointest endosc. 2009;69(7):1409-10. DOI: 10.1016/j.gie.2008.09.039

Stauffer CM. Continuing education activity; 2022. [Cited Jan 31, 2022]. Available:https://www.statpearls.com/ArticleLibrary/viewarticle/19735

Lin SY, Yaow CYL, Ng CH, Wong NW, Tham HY, Chong CS. Different position from traditional left lateral for colonoscopy? A meta-analysis and systematic review of randomized control trials. Chronic Dis Transl Med. 2021;7(1):27-34. DOI: 10.1016/j.cdtm.2020.09.002, PMID 34013177, PMCID PMC8110879.

Medicine JH. Colonoscopy; 2023. [cited Feb 3, 2023]. Available:https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/colonoscopy

Drugs.com. Colonoscopy; 2023. [Cited Feb 3, 2023]. Available:https://www.drugs.com/cg/colonoscopy.html

Informedhealth.org. Colorectal Cancer; 2021.

Yamada Z, Saiki Y, Komori K, Shiomi A, Ueno A, Ito M, et al. Characteristics of anal canal cancer in Japan. Cancer Med. 2022;00:1-9.

Mahadevan V. The anatomy of the rectum and anal canal. Surgery. 2010; 29:1.

Massalou D, Moszkowicz D, Mariage D, Baqué P, Camuzard O, Bronsard N. Is it possible to give a single definition of the rectosigmoid junction? Surg Radiol Anat. 2018;40(4):431-8. DOI: 10.1007/s00276-017-1954-4

Mukai M, Kishima K, Yamazaki M, Aoki H, Izumi H, Yamamoto S, et al. Stage II/III cancer of the rectosigmoid junction: an independent tumor type? Oncol Rep. 2011;26:737-41. DOI: 10.3892/or.2011.1343

Harkins JM, Sajjad H. Anatomy, abdomen and pelvis, sigmoid colon. StatPearls [Internet]. Treasure Islang (FL): StatPearls Publishing. Updated; 2022.

Lee I, Baek S, Kim H, Jo H, Oh N, Ko S. Survival analysis for colon subsite and rectal cancers: Experience from a single surgeon. Korean J Clin Oncol. 2015;11(2): 114-9. DOI: 10.14216/kjco.15019

Huang MJ, Wang XJ, Shao Y, Huang SH, Huang Y, Chi P. Surgical treatment of splenic flexure colon cancer: analysis of short-term and long-term outcomes of three different surgical procedures. Front Oncol. 2022;12:884484.

DOI: 10.3389/fonc.2022.884484

Stelzner S, Hohenberger W, Weber K, West NP, Witzigmann H, Wedel T (3 more authors). Anatomy of the transverse colon revisited with respect to complete mesocolic excision and possible pathways of aberrant lymphatic tumor spread. Int J Colorectal Dis. 2016;31(2):377-84. DOI: 10.1007/s00384-015-2434-0

Bocharova N, Katz I. Absence of ascending colon, persistent transverse colon, and highly movable cecum: A rare congenital abnormality with high risk of volvulus formation. ACS Case Rev. 2020;2(5):36-9.

Coria-Avila GA, Gavrila AM, Ménard S, Ismail N, Pfaus JG. Cecum location in rats and the implications for intraperitoneal injections. Lab Anim. 2007;36(7):25-30. DOI: 10.1038/laban0707-25

Guven H, Koc B, Saglam F, Bayram IA, Adas G. Emergency right hemicolectomy for inflammatory cecal masses mimicking acute appendicitis. World J Emerg Surg. 2014;9(1):7. DOI: 10.1186/1749-7922-9-7

Li M, Ali SM, Umm-a-OmarahGilani S, Liu J, Li Y, Zuo X. Kudo’s pit pattern classification for colorectal neoplasms: A meta-analysis. World Journal of Gastroenterology. 2014;20(35):12649-12656.

Kanao H, Tanaka S, Oka S, Kaneko I, Yoshida S, Arihiro K, et al. Clinical significance of type VI pit pattern subclassification in determining the depth of invasion of colorectal neoplasms. World J Gastroenterol. 2008;14(2):211-7. DOI: 10.3748/wjg.14.211

Kudo S, Tamura S, Nakajima T, Yamano H, Kusaka H, Watanabe H. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc. 1996; 44(1):8-14. DOI: 10.1016/S0016-5107(96)70222-5

Tanaka S, Hayashi N, Oka S, Chayama K. Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy. Clin Endosc. 2013;46(2):138-46. DOI: 10.5946/ce.2013.46.2.138

Tanaka S, Kaltenbach T, Chayama K, Soetikno R. High-magnification colonoscopy (with videos). Gastrointest Endosc. 2006;64(4):604-13. DOI: 10.1016/j.gie.2006.06.007

Mathews AA, Draganov PV, Yang D. Endoscopic management of colorectal polyps: from benign to malignant polyps. World J Gastroenterol. 2021;13(9):356-70. DOI: 10.4253/wjge.v13.i9.356 [PMID: 34630886 DOI: 10.4253/wjge.v13.i9.356].

Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology. 1985;89(2):328-36. DOI: 10.1016/0016-5085(85)90333-6

Vila S, Garcia-Enicas C, Piscoya A, Rios RE, Pinto J, Huerta-Mercado J, et al. [Use of glycerol trinitrate in an ointment for the management of chronic anal fissure at the National Hospital ”Cayetano Heredia”]. Rev Gastroenterol Peru Organo Oficial Soc Gastroenterol Peru. 2009; 29(1):33-9.