International Research Journal of Oncology

Recurrent Malignant Melanoma Eyelid -A Case Report and Review of Literature

Lavanya K. Uthappa

Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

Geeta S. Narayan

Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

Kiran Kumar B. R. *

Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

*Author to whom correspondence should be addressed.

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Abstract

Malignant Melanoma of the eyelid skin arises from the abnormal proliferation of melanocytes. It is a rare condition that accounts for < 1% of all melanomas. They are usually a result of DNA damage from exposure to UVB (290-320). Other common risk factors include Fair skin, red/blond hair, high-density freckling, light eyes (green/ hazel/blue), family history of melanoma or dysplastic nevi, immunosuppression (congenital or acquired), UVA (tanning beds, PUVA therapy). Mutations in CDKN2A, CDK4, XP, BRCA2 genes occurs in 10% of the melanoma.₁ Lower eyelid is the most common location of the eyelid melanoma, where it is approximately 2.6 times more likely to occur than the upper eyelid. Here we present a rare case of recurrent eyelid melanoma in a 62-year-old lady.

Keywords: Nevi, malignant melanoma, metastasis, upper eyelid, radiotherapy

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