A Rare Case Presentation of Adenoid Cystic Carcinoma of the Breast in a 36-Year-Old Fe-male

Aradhana Mohan

Department of Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

Geeta S Narayanan

Department of Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

Kiran Kumar BR *

Department of Radiation Oncology, Vydehi Institute of Medical Sciences and Research Centre, Karnataka, India.

*Author to whom correspondence should be addressed.


Abstract

Background: Primary adenoid cystic carcinoma (ACC) of breast is rarely seen clinically. It is a special subtype of triple-negative breast cancer characterized by low expression of Ki-67, low malignant potential, slow progression and favourable prognosis. To date, treatment for this disease is controversial and no consensus is reached. We analyzed clinical manifestations and pathological characteristics of a primary breast ACC and reported in combination with literature review to promote understanding, diagnosis and treatment of this disease.

Case presentation: We reviewed a case of 36-year-old female with pathologically diagnosed breast ACC and treated at our department. Molecular type was triple negative and Ki-67 expression was low (5/7). Patient underwent Modified Radical Mastectomy with Axillary Lymph node Dissection. She received both adjuvant chemotherapy and adjuvant radiation. At the follow-up of 36 months patient was disease free and was on regular follow up.

Conclusion: Breast ACC is accompanied with favourable prognosis, which is different from typical triple-negative breast cancer. Accurate diagnosis of ACC is particularly important. Multidisciplinary approach should be considered in the management.

Keywords: Breast, adenoid cystic carcinoma, treatment, prognosis, chemotherapy, radiotherapy


How to Cite

Mohan, Aradhana, Geeta S Narayanan, and Kiran Kumar BR. 2025. “A Rare Case Presentation of Adenoid Cystic Carcinoma of the Breast in a 36-Year-Old Fe-Male”. International Research Journal of Oncology 8 (1):1-7. https://doi.org/10.9734/irjo/2025/v8i1169.

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