Metachronous Dual Malignancy in an Indian Albino
Published: 2021-08-10
Page: 228-232
Issue: 2021 - Volume 4 [Issue 2]
B. R. Kiran Kumar *
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
Amrut S Kadam
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
Deepak Sharma
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
V. Chendil
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
J. Rajesh
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
B. K. Raghavendra
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
P. Shylini
Department of Radiation Oncology, Bangalore Medical College and Research Institute, Bangalore-560002, Karnataka, India
*Author to whom correspondence should be addressed.
Abstract
Oculocutaneous albinism (OCA) is the most common inherited pigmentary disorder of the skin which is associated with impaired melanin biosynthesis. Clinical features of OCA are decreased pigmentation of the skin, hair, and eyes. The absence of melanin increases the risk of these patients to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and Squamous cell carcinoma (SCC) are the most common malignancies associated with OC and have been rarely reported. Metachronous malignancies in the OCA have not been reported in the literature. We report one such rare case of Metachronous Basal Cell Carcinoma of the skin and Squamous cell Carcinoma Lung in an Indian Albinism Patient.
Keywords: Oculocutaneous Albinism, Melanin, Skin Carcinoma, Genetic Disorder