Growing Burden of Breast Cancer in Bihar, a State of Eastern India: Epidemiology, Treatment and Outcome
Published: 2022-12-08
Page: 139-147
Issue: 2022 - Volume 5 [Issue 2]
Vijay Pratap Singh *
Department of Surgical Oncology, Savera Cancer and Multispeciality Hospital, India.
Avinash Pandey
Department of Medical Oncology, Savera Cancer and Multispeciality Hospital, India.
Akash Kumar Singh
Department of Surgical Oncology, Savera Cancer and Multispeciality Hospital, India.
Sumantra Sircar
Department of Surgical Oncology, Savera Cancer and Multispeciality Hospital, India.
Rahul Kumar Chaudhary
Department of Surgical Oncology, Savera Cancer and Multispeciality Hospital, India.
Arun Kumar Jha
Department of Clinical Research, Savera Cancer and Multispeciality Hospital, India.
Pranab Kumar Verma
Department of Pathology, Savera Cancer and Multispeciality Hospital, India.
Manish Jaipuriyar
Department of Pathology, Savera Cancer and Multispeciality Hospital, India.
Vishal Mohan Singh
Department of Anesthesia, Savera Cancer and Multispeciality Hospital, India.
Neeta Jha
Department of Administration, Savera Cancer and Multispeciality Hospital, India.
Priyadarshi Ranjan
Department of Oncoplastic Surgery, Savera Cancer and Multispeciality Hospital, India.
Sanjay Kumar
Department of Pathology, Savera Cancer and Multispeciality Hospital, India.
Pratik Anand
Department of Maxillofacial Surgery, Savera Cancer and Multspeciality Hospital, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Worldwide, the incidence and mortality of breast cancer are rising rapidly, and emerging countries are particularly affected by this change. Globally 25%, or 2.1 million cases, of all female cancers diagnosed in 2018 were breast cancer. The leading cause of death for women is breast cancer. The present study was aimed to report the patient demographics, age, histopathology, stage, and status of presentation, compliance with treatment, follow-up, and survival.
Methods: Our cancer centre has evaluated breast cancer data of (n=422) patients over the period of January 2017 to December 2021. Retrospectively database of patients with breast cancer available in our medical records department and Hospital-Based Cancer Registry software were reviewed. The data were analyzed using IBM SPSS 26.0.
Results: A total of 422 breast cancer cases were registered in our hospital. Of these (n=389; 92.18%) had received treatment. This study has reported a good survival rate of 62.21%, patients (n=242; 62.21%) are alive (n=43; 17.77%) survived with disease free, (n=59; 24.38%) with residual disease and patients (n=84; 19.79%) were expired due to disease progression. The outcomes of triple-negative breast cancer were poor and the treatment options are mainly restricted to systemic chemotherapy. Mortality rates reported in triple negative breast cancer were 80.91%.
Conclusion: The survival rates in this study were reported 62.21%. Breast cancer is spreading aggressively in India. Multicentre clinical trials on breast cancer must be carried out in tier two three cities of India. The requirement is for a strong awareness campaign and the efficient implementation of a national cancer screening programme.
Keywords: Bihar, breast cancer, treatment, outcome, survival